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Keflex is a cephalosporin antibiotic and is used to treat bacterial infections of the skin, urinary tract, respiratory tract, bones, and joints. Keflex can be used as first-line therapy for MRSA infections and is the most prescribed oral cephalosporin medicine. Cephalexin is contra-indicated in patients with known allergy to the cephalosporin group of antibiotics. Cephalexin stops or slows the growth of micro-organisms such as bacteria, fungi, or protozoa. Although side effects from Cephalexin are not common, they can occur. Cephalexin is contra-indicated in patients with known allergy to the cephalosporin group of antibiotics. Cephalexin is indicated in the treatment of the following infections due to susceptible micro-organisms respiratory tract infections, bone infections, genitourinary tract infections. The infection. Patients taking other cephalosporin antibiotics can not take additional cephalosporin antibiotics as this is likely to result in an overdose.